Characteristics of Superficially-Porous Silica Particles for Fast HPLC: Some Performance Comparisons with Sub-2- m Particles
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چکیده
منابع مشابه
Fast and Efficient HPLC Separations With Superficially Porous Particles
The current trend in liquid chromatography is towards the achievement of higher kinetic efficiency and shorter analysis time. Different types of column packings are now available for attaining very fast and high resolution separations without changing instruments, worrying about high backpressure or compromising column longevity. In recent developments of particle technology, the use of superfi...
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Large-size (4-5 µm) superficially porous particles yield lower plate heights (e.g., the minimal reduced plate height or hmin ≈ 1.5) than fully porous particles of a similar size when packed into large-bore columns. This property allows for better chromatographic performance without the higher pressures required for smaller particles. This study explores the use of such particles in microfluidic...
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ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2008
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chromsci/46.3.254